Templated nucleoside triphosphate binding to a noncatalytic site on RNA polymerase regulates transcription
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چکیده
منابع مشابه
Allosteric Binding of Nucleoside Triphosphates to RNA Polymerase Regulates Transcription Elongation
The regulation of transcription elongation and termination appears to be governed by the ability of RNA polymerase elongation complexes to adopt multiple conformational states; however, the factors controlling the distribution between these states remain elusive. We used transient-state kinetics to investigate the incorporation of single nucleotides. We demonstrate that E. coli RNA polymerase c...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2011
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1011274108